Die Blutgerinnung ist ein komplexes Geschehen, dessen Abläufe durch vielfältige Aktivierungs- und Inaktivierungsprozesse reguliert werden. Bereits kleinste Störungen im komplizierten Gleichgewicht zwischen Blutstillung und Fibrinolyse können schwerwiegende Folgen wie Blutungen oder Thrombosen nach sich ziehen. In der vorliegenden Einführung in die Physiologie und Pathophysiologie des Gerinnungssystems werden diese komplexen Sachverhalte umfassend und übersichtlich vermittelt:

Die Darstellung der biochemischen und physiologischen Grundlagen und Abläufe der Blutgerinnung erfolgt in strukturierter, leicht verständlicher Form.

Besonderer Wert wird auf die Beschreibung der einzelnen Gerinnungsstörungen – der hämorrhagischen Diathesen und der Thrombophilien – sowie die Methodik der diagnostischen Testverfahren gelegt.

Eine ausführliche Übersicht über alle therapeutischen Optionen folgt dem neuesten Wissensstand.

Für die zweite Auflage wurden zahlreiche Ergänzungen und Verbesserungen eingefügt. Das Kapitel über die direkten oralen Antikoagulanzien wurde auf den aktuellen Stand gebracht.

Durch historische Kapitel sollen die Leistungen von Hämostaseologen gewürdigt werden, die zur Aufklärung des faszinierenden Systems der Gerinnung beigetragen haben. Jeder Leser weiß nach der Lektüre, wie es zum Quick-Wert oder dem Christmas-Faktor gekommen ist. Fakten, die das Erinnern leicht machen.

Das vorliegende Buch ist für Studenten und Ärzte im klinischen Alltag gleichermaßen vorzüglich geeignet.

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